BNP3 Antilichaam [3A6F7C7]

BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.

4879

P16860

P16860

Human

Synthetic peptide corresponding to aa (Glu-Pro-Leu-Gln-Glu-Ser-Pro-Arg-Pro-Thr-Gly-Val-Trp-Cys) of human BNP3.

3A6F7C7

Unconjugated

Primary Antibodies

Growth Factors

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

BNP3 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

NPPB

Natriuretic peptide B

Homo sapiens

Dawson A. Struthers AD. Expert Opin Biol Ther. 2003, Feb, 3 (1) :107-12. Review.

Pfister R. Erdmann E. Schneider CA. Dtsch Med Wochenschr. 2003, May 2, 128 (18) :1007-12.

Gamma-brain natriuretic peptide, BNP-32, BNP

IHC

113836