BNPTAB Antilichaam

This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572) . In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.

79158

Q3T906

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 42-350 of human GNPTAB (NP_077288.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 144kDa

IgG

WB: 1:500 - 1:2000

GNPTAB

293T

N-acetylglucosamine-1-phosphate transferase subunits alpha and beta

Homo sapiens

GNPTA, ICD, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta, GlcNAc phosphotransferase, N-acetylglucosamine-1-phosphate transferase alpha and beta subunits, UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta, UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosamine, glcNAc-1-phosphotransferase subunits alpha/beta, glucosamine (UDP-N-acetyl) -lysosomal-enzyme N-acetylglucosamine phosphotransferase, stealth protein GNPTAB

WB

Liquid