BO-264
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
BO-264 is a potent (IC50 = 188 nM) inhibitor of transforming acidic coiled-coil 3 (TACC3), an important protein involved in microtubule stability and centrosome integrity.1 TACC3 is frequently upregulated in a broad range of cancers. BO-264 displayed significant anticancer activity in greater than 90% of cell lines in the NCI-60 human cancer cell line panel. Active in vivo in mice injected with JIMT-1 and EMT6 breast cancer cells as well as mouse colon cancer xenografts HCT-116 and CT-26.
Unconjugated
Off-white solid
-20°C
Beschrijving
BO-264 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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