Boc-AEVD-CHO (TFA)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Boc-AEVD-CHO TFA is a Caspase 8 inhibitor. Boc-AEVD-CHO TFA significantly increases the frequencies of Nocodazole or methyl methane sulfonate (MMS) induced micronuclei (MN) and micronucleated binucleates (MNCB) in PBMC by inhibiting cell apoptosis. Boc-AEVD-CHO TFA can be used for immune and inflammatory diseases research[1].
12352209
Apoptosis; Caspase
Apoptosis
Inflammation/Immunology
C[C@H](NC(OC(C)(C)C)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](C=O)CC(O)=O)=O)=O)=O.FC(C(O)=O)(F)F.[x]
C22H36N4O10.xC2HF3O2
516.54 (free base)
[1]Decordier I, et al. Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation. Mutagenesis. 2005 May;20 (3) :173-9.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P5834A/
Peptides
No Development Reported
Caspase 8
Beschrijving
Boc-AEVD-CHO TFA is a Caspase 8 inhibitor. Boc-AEVD-CHO TFA significantly increases the frequencies of Nocodazole or methyl methane sulfonate (MMS) induced micr
Specificaties
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