Boc3Arg
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Boc3Arg is the tert-butyl carbamate-protected arginine. Boc3Arg is an efficient tag to induce degradation through directly localizing the protein to the 20S proteasome[1][2].
108787-91-3
12352211
H302, H315, H319, H335
Proteasome
Metabolic Enzyme/Protease
Cancer-Kinase/protease
Cancer
97.0
DMSO : ≥ 200 mg/mL
O=C(O)[C@H](CCC/N=C(NC(OC(C)(C)C)=O)/NC(OC(C)(C)C)=O)NC(OC(C)(C)C)=O
C21H38N4O8
474.55
H302, H315, H319, H335
[1]Sun H, et al. Identification of Boc2Lys-Linked Ethacrynic Acid and Its Analogues As Efficient Glutathione S-Transferase Degraders. ACS Med Chem Lett. 2024 Oct 14;15 (11) :1852-1859.|[2]Marcus J.C. Long, et al. Inhibitor Mediated Protein Degradation. Chemistry & Biology. 2021, 19 (5) : 629-637.
Room Temperature
-20°C, 3 years; 4°C, 2 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-23020/Boc3Arg-SDS-MedChemExpress.pdf
Reference compound1
No Development Reported
Beschrijving
Boc3Arg is the tert-butyl carbamate-protected arginine. Boc3Arg is an efficient tag to induce degradation through directly localizing the protein to the 20S pro
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