Bostrycine

21879-81-2

Others, Antibacterial, Antibiotic

Microbiology/Virology, Others

Bostrycin, an anthraquinone derived from B. alpestre, exhibits a broad spectrum of biological activities including antibacterial, antiproliferative, and phytotoxic effects. This compound demonstrates efficacy against Gram-positive bacteria like methicillin-resistant S. aureus (MRSA), M. tuberculosis, and C. botulinum. Additionally, Bostrycin shows antiproliferative action against A549 lung adenocarcinoma cells, particularly by arresting the cell cycle at the G0/G1 phase and triggering apoptosis within a concentration range of 10 to 30 μM. As a phytotoxin, it causes necrosis in water hyacinth leaves at approximately 7 μg/ml. Furthermore, Bostrycin serves as a protein immobilization cross-linking agent, managing to preserve its bacteriostatic properties when affixed to nonwoven polypropylene fabric.

OC1=C2C(=C(O)C3=C1C(=O)C=C(OC)C3=O)C[C@](C)(O)[C@H](O)[C@H]2O

C16H16O8

336.29

Ice Packs

-20°C