Bosutinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
An ATP-competitive dual Src/Abl kinase inhibitor (IC50 = 1 nM) .1 It potently inhibits the apoptosis-linked STE20 kinases but does not inhibit Kit or PDGFR.2 Bosutinib was found to inhibit 16 of 18 imatinib-resistant mutant forms of Bcr-Abl expressed in murine myeloid cell lines, but did not inhibit T315I and V299L mutants.3 Enhances retinoic acid-induced differentiation of HL-60 leukemia cells.4 Suppresses migration and invasion of human breast cancer cells (IC50 = 250 nM which is also the IC50 for inhibition of cellular Src kinase activity in intact tumor cells) .5
Unconjugated
Off-white solid
-20°C
Beschrijving
Bosutinib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
Hettich Centrifuge Rotanta 460R Refrigerated Large Volume
CEN0703
1 Each
X4RF Refrigerated Centrifuge
75009936
1 Each
Drug Stability Chamber
500-DSC102
1 Unit
Modular Incubator Chamber
MIC-101
1 Unit
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests
Eco Alu MTP (HxD) 6x7=42 plates 35mm, 223x630x135mm
TE15336
1 Piece
Recent gezochte producten
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
X4RF Refrigerated Centrifuge
75009936
1 Each
Low Speed Refrigerated Centrifuge
LX104LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX117LSR
1 Unit
Low Speed Refrigerated Centrifuge
LX124LSR
1 Unit
Blood Bank Refrigerator
LX4000BBR
1 Unit
Blood Bank Refrigerator
LX4002BBR
1 Unit
Blood Bank Refrigerator
LX4003BBR
1 Unit