
Bosutinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
380843-75-4
SKI-606
C07435-1g
Src
Protein Tyrosine Kinase
CN1CCN (CC1) CCCOC2=C (C=C3C (=C2) N=CC (=C3NC4=CC (=C (C=C4Cl) Cl) OC) C#N) OC
C26H29Cl2N5O3
Bosutinib is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy.
2 years -80 in solvent
Beschrijving
Bosutinib Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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