BP242
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PP242 is an ATP-competitive mTORC1/mTORC2 inhibitor (IC50 = 8 nM) displaying high selectivity over PI 3K family kinases (IC50s =0.102 to 2.2 μM) and modest selectivity over PKC family kinases (IC50s =0.049 to 0.198 μM) .1,2 PP 242 (but not rapamycin) induced the death of mouse and human leukemia cells but was much weaker than rapamycin at induction of death of normal lymphocytes.3 Restores lysosomal activity and facilitates clearance of amyloid-β in a mouse model of dry age-related macular degeneration.4 Inhibits glioblastoma cell proliferation, migration, invasiveness, and stemness.5
Unconjugated
Off-white to beige solid
-20°C
Beschrijving
BP242 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
1,4- Dioxane Pure
1041330 500
500 mL
Benzonase ELISA Kit
EG23601S
96 Tests
Not I Restriction Enzyme
B2016623
500 Units
K562-HLA-G0101 Overexpressing Cell Line
RG-1214
5x 10^6
Yeast Poly (A) Polymerase
RNT-006-S
30000 Units
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
Arachis hypogaea lectin (PNA)
05-0116-10mg
10 mg
Anti-APOE2 mouse monoclonal antibody
TD-AB0132
100 µg