BPP 5a

BPP 5a is a bradykinin-potentiating peptide with vasorelaxant activity, which is found in Bothrops jararaca venom. BPP 5a is an angiotensin-converting enzyme (ACE) inhibitor with a Ki value of 400 nM. BPP 5a is promising for research of hypertension and cardiovascular diseases[1].

30505-63-6

12352209

Angiotensin Receptor; Peptide-Drug Conjugates (PDCs)

Antibody-drug Conjugate/ADC Related; GPCR/G Protein

Neuroscience-Neuromodulation

Cardiovascular Disease

O=C([C@H]1NC(CC1)=O)N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C)C(N2[C@@H](CCC2)C(O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O

C30H41N7O7

611.69

[1]Ianzer D, et al. BPP-5a produces a potent and long-lasting NO-dependent antihypertensive effect. Ther Adv Cardiovasc Dis. 2011 Dec;5 (6) :281-95.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P2619/

Peptides

No Development Reported