BPTES
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Potent and selective allosteric1 inhibitor of kidney-type glutaminase (GLS1), IC50 = 3.3 µM2. Selective for GLS1 over GLS2, g-glutamyl transpeptidase and glutamate dehydrogenase. Shuts down an alternative energy-generating glutaminolysis pathway in P493 cells under both glucose deprivation or hypoxia.3 Reduces the growth of P493 cell xenografts by 50% over a 10 day treatment.4 BPTES inhibition of glutamine utilization in cancer cells increases PD-L1 expression.5 Clears senescent cells and improves various age-related disorders in a geriatric mouse model.6
Unconjugated
White to off-white solid
-20°C
Beschrijving
BPTES Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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