BRAL1 Antilichaam

BRAL1 Antibody: BRAL1 is a member a superfamily consisting of several highly homologous hyaluronan and proteoglycan binding link proteins. BRAL1 is predominantly expressed in brain tissue and spinal cord. Like other members in the link-module superfamily, BRAL1 contains an immunoglobulin-like fold and two proteoglycan tandem repeats (PTRs) . Its mRNA expression pattern is similar to other lectican proteoglycans, suggesting that BRAL1 may act to stabilize the binding between the extracellular matrix molecule hyaluronan and brevican. Immunostaining of mouse brain showed BRAL1 expression at P20 in the white matter of the developing cerebellum and in myelinated fiber tracts in the adult brain, suggesting that expression starts when axonal myelination occurs.

60484

Q9GZV7

NP_068589

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Neuroscience

BRAL1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1303 - Human Brain Tissue Lysate

1 mg/mL

BRAL1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

BRAL1 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

IgG

HAPLN2

Cat. No. 10-301 - Human Brain Tissue Slide

Hyaluronan and proteoglycan link protein 2

Homo sapiens

Spicer AP, Joo A, and Bowling Jr. RA. A hyaluronan binding link protein gene family whose members are physically linked adjacent to chrondroitin sulfate proteoglycan core protein genes. J. Biol. Chem.2003; 278:21083-91.

Hirakawa S, Oohashi T, Su W-D, et al. The brain link protein-1 (BRAL1) : cDNA cloning, genomic structure, and characterization as a novel link protein expressed in adult brain. Biochem. Biophys. Res. Comm.2000; 276:982-9.

Oohashi T, Hirakawa S, Bekku Y, et al. Bral1, a brain-specific link protein, colocalizing with the versican V2 isoform at the nodes of Ranvier in developing and adult mouse central nervous systems. Mol. Cell Neurosci.2002; 19:43-57.

BRAL1 Antibody: BRAL1, Hyaluronan and proteoglycan link protein 2, Brain link protein 1

ELISA, WB, IHC-P, IF

11141887

Liquid