BRAT1 Antilichaam

The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex) . The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.

221927

Q6PJG6

Human, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 652-821 of human BRAT1 (NP_689956.2) .

Unconjugated

Primary Antibodies

Other

Affinity purification

A-431

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 95kDa

IgG

BRAT1

HeLa

Jurkat

BRCA1 associated ATM activator 1

Homo sapiens

BAAT1, C7orf27, NEDCAS, RMFSL, BRCA1-associated ATM activator 1, BRCA1-associated protein required for ATM activation protein 1, HEAT repeat-containing protein C7orf27

WB, IHC

Liquid