BRD2 Antilichaam

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.

6046

P25440

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BRD2 (NP_001186385.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 110kDa

IgG

WB: 1:500 - 1:2000

BRD2

Bromodomain containing 2

Homo sapiens

BRD2, FSH, NAT, RNF3, FSRG1, RING3, D6S113E

WB

Liquid