BRWD1 Antilichaam

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.

54014

Q9NSI6

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human BRWD1 (NP_001007247.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 263kDa

IgG

WB: 1:1000 - 1:3000

BRWD1

Jurkat

SGC-7901

NIH/3T3

Bromodomain and WD repeat domain containing 1

Homo sapiens

Bromodomain and WD repeat domain containing 1, bromodomain and WD repeat-containing protein 1, BRWD1, C21orf107, FLJ43918, N143, OTTHUMP00000068796, OTTHUMP00000068797, OTTHUMP00000068928, OTTHUMP00000207967, transcriptional unit N143, WD repeat protein WDR9-form2, WD repeat-containing protein 9, WDR9 , WDR9

WB

Liquid