BSCL2 Antilichaam

This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2) .

26580

Q96G97

Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human BSCL2 (NP_116056.3) .

Unconjugated

Primary Antibodies

Neuroscience, Obesity

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 46kDa

IgG

WB: 1:500 - 1:2000

BSCL2

Mouse lung

Mouse testis

Rat brain

Rat testis

BSCL2 lipid droplet biogenesis associated, seipin

Homo sapiens

GNG3LG, HMN5, PELD, SPG17, seipin, BSCL2, seipin lipid droplet biogenesis associated, Berardinelli-Seip congenital lipodystrophy 2 (seipin), Bernardinelli-Seip congenital lipodystrophy type 2 protein

WB

Liquid