BTB-1
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A selective, ATP-competitive and reversible inhibitor of mitotic kinesin Kif18A, IC50=1.7 M.1,2 Binds to an allosteric site near Kif18A loop 5 preventing a range of conformational changes thereby blocking motor function.3 Inhibits the differentiation of mouse bone marrow cells to dendritic cells.4 Suppresses the replication of influenza A virus, inhibiting activation of AKT, p38 MAPK, SAPK and RanBP3 leading to the prevention of nuclear export of viral ribonucleoprotein complexes. Greatly improves the viability of IAV-infected mice.5
Unconjugated
White or off-white solid
RT
Beschrijving
BTB-1 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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