BTBD14A Polyklonale Antilichaam

BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

BTB POZ domain containing 14A; BTB domain containing 14A; BTB/POZ domain containing protein 14A; BTB/POZ domain-containing protein 14A; BTBD 14A; BTBD14; NAC-2; NACC2; NACC2_HUMAN; Nucleus accumbens-associated protein 2.

54813

Nucleus

401-500/587

BTBD14A

Unconjugated

KLH conjugated synthetic peptide derived from human BTBD14A

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

1µg/µl

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

54813

Human, Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken