BTX-A51
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2079068-74-7
Casein Kinase inhibitor A51
CDK
Cell Cycle
C18H25ClN6
BTX-A51 (Casein Kinase inhibitor A51) is a first-in-class oral and potent inhibitor of casein kinase 1α (CK1α) and cyclin dependent kinase (CDK7/9) with an IC50 of 17 nM for CK1α and Kd of 1.3 nM and 4 nM for CDK7 and CDK9, respectively. It induces apoptosis of leukemic cells by activating p53 and inhibiting expression of Mcl1 and can be used in Acute myeloid leukemia (AML) cancer research.
Beschrijving
BTX-A51 Beschikbaar in 25 mg. Bestel eenvoudig online met snelle levering.
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