BubR1 (BUB1B) Mouse Monoclonal Antibody [Kloon ID: LBI6E5]

This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Carrier-free (BSA/glycerol-free) BUB1B mouse monoclonal antibody, clone LBI6E5

Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1

Homo sapiens BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), mRNA.

701

O60566

Unconjugated

Cell cycle

Cell cycle

WB: 1:200 - 1:1000, IHC 1:50, IF 1:100, Flow 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protein Kinase, Stem cell - Pluripotency

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

BUB1B

https://www.ncbi.nlm.nih.gov/gene/?term=701

https://www.uniprot.org/uniprot/O60566