Buparlisib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Potent pan-Class I PI3-kinase inhibitor (IC50’s: p110α = 52 nM, p110ß = 166 nM, p110δ = 116 nM. P110g = 262 nM) .1,2 It inhibited microtubule dynamics at in vitro concentrations >1µM and doses above 50mg/kg in mice.3 Buparlisib lead to a precipitous drop in DNA synthesis in a mouse model of BRCA1-linked triple-negative breast cancer with less affect in normal tissue.4
Unconjugated
White solid
-20°C
Beschrijving
Buparlisib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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Not I Restriction Enzyme
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K562-HLA-G0101 Overexpressing Cell Line
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0.05 mL
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ROSL-I
1 set
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1021
1 Kit
OSR1 (Oxidative Stress Responsive 1)
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0.1 mL
Oxidative Stress Combo Assay Cell Kit
EA-7006
1 Each
Oxidative Stress Combo Assay Blood Kit
EA-7007
1 Each
Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
OSR1 (Oxidative Stress Responsive 1)
O8054
100 µL