Buteïne-tetramethylether
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Butein tetramethyl ether (Compound 20) is a potent and selective breast cancer resistance protein/ATP-binding cassette subfamily G member 2 (BCRP/ABCG2) inhibitor. Butein tetramethyl ether has inhibitory potencies against MCF-7 MX and MDCK BCRP cells with IC50 values of 2.2 and 1.03 μM, respectively. Butein tetramethyl ether is promising for research of cancers[1].
155048-06-9
12352005
BCRP
Membrane Transporter/Ion Channel
Cancer
COC(C=C1/C=C/C(C2=C(C=C(C=C2)OC)OC)=O)=C(C=C1)OC
C19H20O5
328.36
[1]Juvale K, et al. Investigation of chalcones and benzochalcones as inhibitors of breast cancer resistance protein. Bioorg Med Chem. 2012 Jan 1;20 (1) :346-55.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W082856A/
Reference compound1
No Development Reported
Beschrijving
Butein tetramethyl ether (Compound 20) is a potent and selective breast cancer resistance protein/ATP-binding cassette subfamily G member 2 (BCRP/ABCG2) inhibit
Specificaties
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