Butriptyline (hydrochloride)

Butriptyline (Butriptylene) hydrochloride is an orally active tricyclic antidepressant that slightly enhances central 5-HT effects. Butriptyline hydrochloride does not inhibit brain norepinephrine uptake. Butriptyline hydrochloride can be used for depression research[1][2][3].

5585-73-9

Butriptylene (hydrochloride)

12352005

5-HT Receptor

GPCR/G Protein; Neuronal Signaling

Neurological Disease

CC(CN(C)C)CC1C2=C(C=CC=C2)CCC3=C1C=CC=C3.Cl

C21H28ClN

329.91

[1]Pugsley TA, et al. Effect of butriptyline on the brain uptake mechanisms for noradrenaline and 5-hydroxytryptamine. J Pharm Pharmacol. 1974 Oct;26 (10) :778-8.|[2]Dulloo AG, et al. Screening of drugs for thermogenic anti-obesity properties: antidepressants. Ann Nutr Metab. 1987;31 (2) :69-80.|[3]Molinengo L, et al. The action of imipramine, amitriptyline, doxepin and butriptyline in an operant conditioning schedule. Psychopharmacologia. 1972;24 (2) :247-57.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-A0175A/

Reference compound1

No Development Reported