Butyrolacton Ia
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Butyrolactone Ia is the inhibitor for the NO production with an IC50 of 18 μM. Butyrolactone Ia inhibits LPS -induced mRNA expression of iNOS and the inflammatory cytokine IL-1β. Butyrolactone Ia modulates autophagy in HeLa cells, and exhibits immune suppressive activity[1].
942986-92-7
12352005
Autophagy; Interleukin Related; NO Synthase
Autophagy; Immunology/Inflammation
Cancer-programmed cell death
Inflammation/Immunology
OC([C@]1(C(C2=CC=C(C=C2)O)=C(C(O1)=O)O)CC3=CC(C/C=C(C)\C)=C(C=C3)O)=O
C23H22O7
410.42
[1]Ujie Y, et al., Aspergillus terreus IFM 65899-THP-1 cells interaction triggers production of the natural product butyrolactone Ia, an immune suppressive compound. Sci Rep. 2024 Nov 16;14 (1) :28278.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N15226/
Natural Products
No Development Reported
Beschrijving
Butyrolactone Ia is the inhibitor for the NO production with an IC50 of 18 μM. Butyrolactone Ia inhibits LPS -induced mRNA expression of iNOS and the inflammato
Specificaties
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