BW-534U87
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
BW-534U87 is an orally active adenosine A1 receptor agonist and competitive adenosine deaminase (ADA) inhibitor (Ki=7 μM) . BW-534U87 elevates brain adenosine levels and suppresses epileptiform activity. BW-534U87 demonstrate anticonvulsant efficacy in animal seizure models. BW-534U87 is promising for research of epilepsy and adenosine-related neuropsychiatric disorders[1].
143153-93-9
12352005
H302-H315-H319-H335
Adenosine Receptor
GPCR/G Protein
Neurological Disease
FC1=CC=CC(F)=C1CN2N=NC3=C2C=CN=C3N.Cl
C12H10ClF2N5
297.69
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
[1]Southam E, et al. Broad spectrum anticonvulsant activity of BW534U87: possible role of an adenosine-dependent mechanism. Pharmacol Biochem Behav. 2002 Dec;74 (1) :111-8.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19130/
Reference compound2
Phase 2
Adenosine A1 receptor (A1R)
Beschrijving
BW-534U87 is an orally active adenosine A1 receptor agonist and competitive adenosine deaminase (ADA) inhibitor (Ki=7 μM) . BW-534U87 elevates brain adenosine l
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