BX-795
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
702675-74-9
C16223-25mg
IκB/IKK
NF-κB
C1CCN (C1) C (=O) NC2=CC=CC (=C2) NC3=NC=C (C (=N3) NCCCNC (=O) C4=CC=CS4) I
C23H26IN7O2S
BX-795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3β more than 100-fold selectivity observed for PDK1. BX-795 modulates autophagy via inhibiting ULK1. BX-795 also is a potent TBK1 inhibitor that blocks both TBK1 and IKKε with IC 50 values of 6 nM and 41 nM, respectively.
2 years -80 in solvent
Beschrijving
BX-795 Beschikbaar in 25 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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