C-DIM 8
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
C-DIM 8 is an antagonist of the orphan nuclear receptor Nur77 (NR4A1, TR3) .1 Induces reactive oxygen species and ER stress in pancreatic cancer cells.2 C-DIM 8 mimics the effect of Nur77 knockdown in non-small-cell lung cancer A549 and H460 cells, inhibiting cell growth and inducing apoptosis which was accompanied by decreased expression of survivin and inhibition of mTORC1 signaling.3 Inhibits the expression of β1- and β3-integrin and blocks integrin-dependent breast cancer cell migration.4 Decreases expression of the histone methyltransferase G9A (EHMT2) in a variety of cancer cell lines.5
Unconjugated
Pink solid
-20°C
Beschrijving
C-DIM 8 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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