C10orf27 Polyklonale Antilichaam, APC-vervoeging

C10orf27, also known as spatial, is a 351 amino acid cytoplasmic protein belonging to the spatial family. C10orf27 is suggested to play a role in spermatid differentiation. Existing as two alternatively spliced isoforms, C10orf27 is widely expressed in multiple tissues, including brain, thymus and testis. C10orf27 may be associated with multiple sclerosis (MS) susceptibility and pathogenesis. MS is an inflammatory disease that causes gradual destruction of myelin in the central nervous system. C10orf27 is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.

C10orf27; chromosome 10 open reading frame 27; FLJ32820; Stromal protein associated with thymii and lymph node homolog; stromal protein associated with thymii and lymph nodes; TBATA_HUMAN; SPATIAL; TBATA; thymus, brain and testes associated

219793

Q96M53

Human, Mouse, Rat

31-130/351

C10orf27

APC

KLH conjugated synthetic peptide derived from human C10orf27/SPATIAL

WB, IF

Purified by Protein A.

650nm/660nm

1µg/µl

WB (WB=1:500-2000), IF (IF=1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

219793