C12orf32 (NM 031465) Humaan Recombinant Proteïne

Plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase. Recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in a ATR-dependent manner. Required for the progression of the G1 to S phase transition. Plays a role in the stimulation of CHEK1 phosphorylation.[UniProtKB/Swiss-Prot Function]

Purified recombinant protein of Human chromosome 12 open reading frame 32 (C12orf32), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Chromosome 12 open reading frame 32; HKMT1188; HKMT1188, MGC13204; MGC13204

83695

Q9BSD3

NM_031465

12p13.33

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

26.5 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

C12orf32

Human

NP_113653

https://www.ncbi.nlm.nih.gov/gene/83695

https://www.uniprot.org/uniprot/Q9BSD3

https://www.ncbi.nlm.nih.gov/nuccore/NM_031465

https://www.ncbi.nlm.nih.gov/nuccore/NP_113653