C12ORF54 Polyklonale Antilichaam, RBITC Vervoeging

Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf54 gene product has been provisionally designated C12orf54 pending further characterization.

MGC35033; C12orf54; Chromosome 12 open reading frame 54; CL054_HUMAN; HSD 29; HSD 30; HSD29; Uncharacterized protein C12orf54.

121273

Human, Mouse, Rat

1-80/127

C12ORF54

RBITC

KLH conjugated synthetic peptide derived from human C12ORF54

WB, IF

Purified by Protein A.

570nm/595nm

1µg/µl

WB (WB=1:500-2000), IF (IF=1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

121273