C13orf38 Polyklonale Antilichaam, AbBy FluorTM 488 Vervoeging

Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. The LOC728591 gene product has been provisionally designated LOC728591 pending further characterization.

FLJ57222; Chromosome 13 open reading frame 38; CM038_HUMAN; FLJ13506; FLJ29024; Hypothetical protein LOC728591; RP11-251J8.1; UPF0594 protein C13orf38.

Human

121-214/214

C13orf38

AbBy Fluor™ 488

KLH conjugated synthetic peptide derived from human C13orf38

WB, IF (IHC-P)

Purified by Protein A.

499nm/519nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Mouse, Rat, Rabbit