C14-490
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2639634-82-3
Liposome
Metabolism
C14-490 is an ionizable cationic lipid (pKa= 5.94) utilized in the synthesis of lipid nanoparticles (LNPs) . These LNPs serve as a platform for subsequent gene editing studies in hematopoietic stem cells (HSCs) in utero. C14-490 LNPs encapsulate SpCas9 mRNA and TTR sgRNA, employing an optimized B5 formulation parameter, and are further enhanced by the surface attachment of CD45 antibody F (ab’) 2 fragments to create Systemically Targeted Editing Mechanism LNPs (STEM LNPs) .
OC(CN(CCN1CCN(CC1)CC(OCC)CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)CC(OCC)CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)CCCCCCCCCCCC
C86H177N5O7
1393.35
Ice Packs
-20°C
Beschrijving
C14-490 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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