
C14orf106 Polyklonale Antilichaam
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.
Chromosome 14 open reading frame 106; HsKNL-2; KIAA1903; Kinetochore-associated protein KNL-2 homolog; M18BP1; Mis18-binding protein 1; MIS18BP1; P243; Putative protein p243 which interacts with transcription factor Sp1; Uncharacterized potential DNA binding protein C14orf106; M18BP_HUMAN.
• Rabbit
Human, Mouse, Rat
32-130/1132
C14orf106
• Polyclonal
• IgG
Unconjugated
KLH conjugated synthetic peptide derived from human KNL2/C14orf106
ELISA, IHC-P, IHC-F, IF, ICC/IF
Purified by Protein A.
1µg/µl
ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:100-500), ICC/IF (ICC/IF=1:100-500)
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Beschrijving
C14orf106 Polyklonale Antilichaam Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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