C18orf1 Polyklonale Antilichaam, APC-Cy5,5 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.
C18orf1; Low-density lipoprotein receptor class A domain-containing protein 4; LDLRAD4
753
O15165
Lumenal
• Rabbit
Human
6-100/306
C18orf1
• Polyclonal
• IgG
APC-Cy5.5
KLH conjugated synthetic peptide derived from human C18orf1
WB, IF (IHC-P)
Purified by Protein A.
650nm/694nm
1µg/µl
WB (1:300-5000), IF (IHC-P) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
753
Mouse, Rat, Cow, Sheep
Beschrijving
C18orf1 Polyklonale Antilichaam, APC-Cy5,5 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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