C19orf2 Antilichaam - middengebied HRP (ARP50771_P050-HRP)

URI1, prefoldin-like chaperone

RMP, URI, NNX3, C19orf2, PPP1R19

8725

Q6NX55

NP_604431

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human C19orf2

The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

RPAP3; UBC; ITCH; NEDD4; ATF7; TTI1; RUVBL1; RPS6KB1; PPP1CC; HSP90AA1; APP; UXT; RPAP2; GPN1; RUVBL2; STAP1; POLR2E; URI1; DMAP1; GTF2F2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that URI1 is expressed in Hela, HepG2, MCF7

0.5 mg/ml

Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 80%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

55kDa

Djouder, N., (2007) Mol. Cell 28 (1), 28-40

Wet Ice

495

URI1

URI1

Rabbit

Chromosome 19 open reading frame 2 EMBL AAH67259.1

NM_134447

NGEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCS