C19ORF6 Antilichaam - middengebied HRP (ARP34137 T100-HRP)

Chromosome 19 open reading frame 6

MBRL, ASBABP1, C19orf6, R32184_3, MEMBRALIN

91304

Q4ZIN3-2

NP_219488

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human C19ORF6

Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species. The membralin gene contains 11 exons which encode at least two spliced variants in human cancer. The long form of membralin (membralin-1) comprises all 11 exons, encoding a protein of 620-amino acids long and the short form of membralin (membralin-3) contains all exons except for exon 10, encoding a protein of 408 amino acids. Expression of different membralin isoforms depends on tissue type. The long form, membralin-1, is expressed in ovarian and colorectal carcinomas but not in breast or pancreatic carcinomas, which express only the short splice form, membralin-3. Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas

ADRB2; UBC; TMEM173; ARSE

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

TMEM259 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

46kDa

Andersson, O., et al., (2002) Brain Res. Gene Expr. Patterns 1 (3-4), 205-212

Wet Ice

408

TMEM259

TMEM259

Rabbit

Membralin

NM_033420

YDDILMSSVKGLAENEENKGFLRNVVSGEHYRFVSMWMARTSYLAAFAIM