C1orf187/Draxine Polyklonale Antilichaam, FITC-vervoeging

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.

AGPA3119; C1orf187; Chromosome 1 open reading frame 187; Dorsal repulsive axon guidance protein; DRAXI_HUMAN; Draxin; Neucrin; UNQ3119.

374946

Human, Mouse, Rat

261-349/349

C1orf187/Draxin

FITC

KLH conjugated synthetic peptide derived from human C1orf187

WB, IF

Purified by Protein A.

494nm/518nm

1µg/µl

WB (1:300-5000), IF ()

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

374946