C1orf67 Polyklonale Antilichaam, AbBy FluorTM 405 Vervoeging

Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. Axonemal dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNAH14 (dynein, axonemal, heavy chain 14), also known as C1orf67 or HL18, is a 3,507 amino acid member of the dynein heavy chain protein family. DNAH14 is one of the force generating protein of respiratory cilia and may be involved in sperm motility through sperm flagellar assembly.

Chromosome 1 open reading frame 67; Coiled coil domain containing protein C1orf67; Hypothetical protein LOC200095; MGC149665; MGC149666; MGC27277; MGC51214; DYH14_HUMAN.

127602

Human

201-300/3507

C1orf67

AbBy Fluor™ 405

KLH conjugated synthetic peptide derived from human C1orf67/DNAH14

IF (IHC-P)

Purified by Protein A.

401nm/421nm

1µg/µl

IF (IHC-P) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

127602