C1QA Antilichaam

C1q. C1q associates with the proenzymes C1R and C1S to yield C1, the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.

712

P02745

NP_057075.1 (A), NP_000482.2 (B), NP_758957.1 (C)

Human

Human plasma C1q protein

Unconjugated

Primary Antibodies

Signal Transduction, Innate Immunity, Neuroscience

Antigen affinity-purified

1 mg/mL

Phosphate-Buffered Saline. No preservatives added.

None

Blue Ice

C1QA antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

26 kDa (calculated)

C1q antibody can be used for the detection of C1q by Western blot, ELISA, may also work for IHC and ICC.

C1QA

Complement component 1, q subcomponent, A chain

Homo sapiens

Leigh, L. E. et al. C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signaling mechanisms Biochem. J. 330 (Pt 1), 247-254 (1998) .

Complement C1q subcomponent subunit A

ELISA

7705753 (A), 11038662 (B), 27363488 (C)

Liquid