C22orf28 Polyklonale Antilichaam, APC-Cy5,5 Vervoeging

HSPC117, also known as C22orf28, is a 505 amino acid protein that is encoded by a gene which maps to human chromosome 22. A highly homologous protein identified in rodents, FAAP (focal adhesion associated protein), encoded by murine D10Wsu52e gene, has been suggested to play a role in regulating cell adhesion dynamics. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

FAAP; Ankyrin repeat domain 54; C22orf28; Chromosome 22 open reading frame 28; DJ149A16.6; HSPC117; Hypothetical protein LOC51493; Novel protein HSPC117; RP1-149A16.6; RTCB_HUMAN; tRNA-splicing ligase RtcB homolog.

51493

Mouse

411-505/505

C22orf28

APC-Cy5.5

KLH conjugated synthetic peptide derived from human HSPC117/C22orf28

WB, IF (IHC-P)

Purified by Protein A.

650nm/694nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

51493

Human, Rat, Cow, Sheep, Pig, Horse, Rabbit