C3a Mouse (TECO®)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
C3 is central to the classical, alternative and lectin pathways of complement activation. The synthesis of C3 is tissue‐specific and is modulated in response to a variety of stimulatory agents. During complement activation, C3 is proteolytically cleaved resulting in release of the anaphylatoxic peptide C3a. C3a is a small polypeptide consisting of 74 amino acids. C3a itself is very short‐lived and in serum cleaved rapidly into the more stable C3a‐desArg (also called acylation stimulating protein, ASP) . Therefore, measurement of C3a‐desArg allows reliable conclusions about the level of complement activation in the samples.
ELISA
25 μL (plasma or serum, dilute 1:100)
31 – 500 ng/mL
LOD: 4.5 ng/mL LLOQ: 0.023 ng/mL
Mouse
3 Hours
Beschrijving
C3 is central to the classical, alternative and lectin pathways of complement activation. The synthesis of C3 is tissue‐specific and is modulated in response to
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