C4BPB Antilichaam - N-terminaal gebied: Biotine (ARP33814 P050-Biotin)

Complement component 4 binding protein, beta

C4BP

725

P20851

NP_000707

Human, Dog, Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human C4BPB

C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.

UBC; PROS1

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

C4BPB is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Dog: 86%; Human: 100%; Pig: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

28kDa

Anderson, N.L., et al., (2004) Mol. Cell Proteomics 3 (4), 311-326

Wet Ice

252

C4BPB

C4BPB

Rabbit

C4b-binding protein beta chain

NM_000716

CCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLV