C5A

811418-15-2

HIV Protease, HCV Protease

Proteases/Proteasome, Microbiology/Virology

C5A is an antimicrobial peptide compound with activity against Hepatitis C Virus (HCV) and HIV. It disrupts the membrane integrity of HIV viral particles as well as the conical capsid core that encloses the viral genome. C5A inhibits in vitro infectivity of various primary HIV isolates across different primary target cells. Additionally, C5A provides protection to mice from vaginal and rectal HIV infections.

C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC([C@H](CO)N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CC(O)=O)=O)[C@H](CC)C)=O)C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CCCCN)C(O)=O)=O)=O)CC(O)=O)=O)CO)=O)CC(C)C)=O)C(C)C)=O)CCC(O)=O)=O)CS)=O)[C@H](CC)C)=O)=O)CC(O)=O)=O)C=6C=7C(NC6)=CC=CC7

C109H155N25O29S

2311.61

Ice Packs

-20°C