C6 Ceramide-13C2, d2

C6 Ceramide-13C2, d2 (C6-Cer-13C2, d2) is the deuterium labeled and 13C-labeled C6 Ceramide. C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis, inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects[1][2][3][4][5].

C6-Cer-13C2, D2; N-Hexanoylsphingosine-13C2, d2

12352211

Apoptosis; Isotope-Labeled Compounds

Apoptosis; Others

Cancer

CCCCCCCCCCCCC/C=C/[C@H]([13C@H]([13C]([2H])(O)[2H])NC(CCCCC)=O)O

C22 13C2H45D2NO3

401.63

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W766368/

Isotope-Labeled Compounds

No Development Reported