C8orf42 Polyklonale Antilichaam, AbBy FluorTM 350 Vervoeging

Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf42 gene product has been provisionally designated C8orf42 pending further characterization.

C8orf42; TDRP_HUMAN; Protein INM01; Protein TDRP; Uncharacterized protein C8orf42.

157695

Cytoplasm, Nucleus

Rat

51-150/185

C8orf42

AbBy Fluor™ 350

KLH conjugated synthetic peptide derived from human C8orf42

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

346nm/442nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

157695

Human, Mouse