C8orf45 Polyklonale Antilichaam, AbBy FluorTM 555 Vervoeging

Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf45 gene product has been provisionally designated C8orf45 pending further characterization.

C8orf45; Chromosome 8 open reading frame 45; FLJ25692; Minichromosome maintenance complex component like; Uncharacterized protein C8orf45; MCMD2_HUMAN.

157777

Cytoplasm, Nucleus

151-250/681

C8orf45

AbBy Fluor™ 555

KLH conjugated synthetic peptide derived from human C8orf45

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

553nm/568nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

157777

Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit