C9orf173 Polyklonale Antilichaam, Biotinevervoeging

C9orf173 (chromosome 9 open reading frame 173) is a 389 amino acid protein that exists as four alternatively spliced isoforms. The gene encoding C9orf173 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X, Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

C9orf173; Chromosome 9 open reading frame 173; CI173_HUMAN; Uncharacterized protein C9orf173.

441476

Cytoplasm, Nucleus

Mouse

201-300/389

C9orf173

Biotin

KLH conjugated synthetic peptide derived from human C9orf173

WB, ELISA

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C for 12 months.

441476

Human, Rat, Dog