C9orf40 Polyklonale Antilichaam, AbBy FluorTM 350 Vervoeging

Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X, Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf40 gene product has been provisionally designated C9orf40 pending further characterization.

C9orf40; Chromosome 9 open reading frame 40; CI040_HUMAN; FLJ10110; FLJ25795; Hypothetical protein LOC55071; Uncharacterized protein C9orf40.

55071

Cytoplasm, Nucleus

101-194/194

C9orf40

AbBy Fluor™ 350

KLH conjugated synthetic peptide derived from human C9orf40

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

346nm/442nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

55071

Human, Mouse, Rat, Cow, Sheep, Pig, Rabbit