Cabozantinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Novel inhibitor of c-met and VEGFR2 kinase activity, IC50=3.5 nm and 35 pM respectively.1 Inhibits MET-activating kinase domain mutations Y1248H, D1246N or K1262R, IC50=3.8, 11.8 and 14.6 nM respectively. In cellular assays it inhibits the following kinases: MET, VEGF2, KIT, FLT3 and AXL, IC50=7.8, 1.9, 5.0, 7.5 and 42 μM respectively.1 Eliminated approximately 80% of vasculature in spontaneous pancreatic islet tumors over 7 days in a mouse model.2 Clinically useful anticancer agent.3
Unconjugated
White solid
-20°C
Beschrijving
Cabozantinib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
Drug Stability Chamber
500-DSC102
1 Unit
Modular Incubator Chamber
MIC-101
1 Unit
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests
Eco Alu MTP (HxD) 6x7=42 plates 35mm, 223x630x135mm
TE15336
1 Piece
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Recent gezochte producten
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
BDBV Nucleoprotein Recombinant Protein (N-His)
VK059012-01
50 µg
KBFP720 700L Stability Chamber
CHA3020
1 Each
KBFLQC240 247L Stability Chamber
CHA3022
1 Each
KBF1020 1020L Stability Chamber
CHA3024
1 Each
Stability Chamber KBFP240 247L
CHA3030
1 Each
Drug Stability Chamber
150-DSC100
1 Unit
Drug Stability Chamber
150-DSC200
1 Unit