
Cabozantinib (XL184)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
849217-68-1
BMS-907351
C07536-5mg
C-Met
Protein Tyrosine Kinase
COC1=CC2=C (C=CN=C2C=C1OC) OC3=CC=C (C=C3) NC (=O) C4 (CC4) C (=O) NC5=CC=C (C=C5) F
C28H24FN3O5
Cabozantinib (XL184) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway.
2 years -80 in solvent
Beschrijving
Cabozantinib (XL184) Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten

Human Sertoli Cell Complete Medium
MBS2576755-01
100 mL

Urobilinogen protein
MBS5303823-01
100 mg

AffiniPure Goat Anti-Rabbit IgG H&L, HRP conjugated
GTR17765564-01
100 µL

Pribolab® Automatic Immunoaffinity Column Purification System
HWEQ-IM 5050
1 Unit

OneTaq Hot Start 2X Master Mix with GC Buffer
NEB M0485L
500 Reactions

HyperLadder 1kb
BIO-33053
100 Lanes

MicroMolar UDP assay kit - 100 assays
MUD100K
100 Assays

MEM Amino Acids Solution (50x) w/o: L-Glutamine
P08-30100
100 mL
Recent gezochte producten

Anti-Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Polyclonal Antibody
E-AB-V1109-01
20 µL

Anti-Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Monoclonal Antibody
E-AB-V1108-01
20 µL

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPAC57A10.07 Polyclonal Antibody
MBS7150018
Inquire

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPAC15A10.07 Polyclonal Antibody
MBS7180894
Inquire

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPBC20F10.07 Polyclonal Antibody
MBS7181630
Inquire

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPCC1840.07c Polyclonal Antibody
MBS7181798
Inquire

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPBC18H10.07 Polyclonal Antibody
MBS7182317
Inquire

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPBC21B10.07 Polyclonal Antibody
MBS9013560
Inquire
